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In addition, the protective effects of both a recombinant adiponectin injection in ob/ob mice and metformin administration against NAFLD have been attributed, at least in part, to the inhibition of hepatic TNF expression 24,25

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Mitochondria are abundant both in the brain and muscles

Alpha lipoic acid is another important antioxidant that increases glutathione levels in a couple of ways: it is able to regenerate oxidized (i.e., used) glutathione back to its usable form, in addition to providing a continuous source of cysteine and increasing the uptake of cysteine into cells, where it increases glutathione production within the cell